POCD
Conditions
Interventions
NIRS monitoring and steering group:Guidance based on NIRS monitoring includes measures to regulate the general circulation (blood pressure, heart rate and pulse oxygen saturation, etc.), increase oxyg
Conventional group:Routine regulation to maintain normal circulation and oxygenation, maintain appropriate body temperature, hemoglobin levels, internal environment, and depth of anesthesia. (NIRS mon
Sponsors
Zigong Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: (a) Subject's voluntary and signed informed consent for this test; (b) age >60 years; (c) ASA classification ?-?; (d) Orthopedic surgery is required under general anesthesia and is expected to take >=1 hour.
Exclusion criteria
Exclusion criteria: (a) Preoperative history of cognitive impairment, mental and neurological diseases, cerebrovascular diseases, severe visual and hearing impairment; (b) recent use of neuropsychiatric drugs; (c) The last hemoglobin before surgery was less than 90g/L; (d) Skin infections or defects at the monitoring site affecting the monitoring.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative cognitive dysfunction, POCD; | — |
Secondary
| Measure | Time frame |
|---|---|
| score of mini-mental state examination (MMSE);incidence acute kidney injury (AKI) ;incidence of postoperative incision infection; | — |
Countries
China
Contacts
Public ContactYeying Zheng
Zigong Fourth People's Hospital
Outcome results
None listed