Non Alcoholic Fatty Liver Disease
Conditions
Interventions
control group:Bicyclol Tablets,po, 50 mg/each dose, 3 times/day
intervention group:Bicyclol Tablets,po, 50 mg/each dose, 3 times/day + Live Combined Bacillus Subtilis and Enterococcus Faecium Enteric-coated Capsules ,po, 500 mg/each dose, 3 times/day
Sponsors
Taizhou People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-80 years old, gender is not limited (including 18 years old and 80 years old) (2) Diagnostic criteria are based on the 2010 Guidelines for the Diagnosis and Treatment of Non-Alcoholic Fatty Liver Disease. (3) Subjects have no history of alcohol abuse or the equivalent amount of ethanol is less than 140g per week; (4) Subjects' clinical information is complete; (5) Subjects were informed and agreed to the content of this study.
Exclusion criteria
Exclusion criteria: (1) The subject has alcoholic fatty liver or viral fatty liver; (2) Subjects with hepatocellular carcinoma or in the compensated stage of cirrhosis; (3) The subject has primary diseases of the liver, kidney, lung and endocrine; (4) The subject is pregnant or breastfeeding; (5) The subject has been treated with medications that affect gastrointestinal motility, such as fructose, microecological agents, and antibiotics, in the 4 weeks prior to enrolment; (6) The subject has poor medication compliance and is unable to take medication on time as prescribed by the physician; (7) Subjects with mental disorders or communication disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase;Aspartate Aminotransferase ; | — |
Secondary
| Measure | Time frame |
|---|---|
| total cholesterol;triglyceride; ?-Glutamyl Transferase ;blood glucose;urea nitrogen;creatinine; Colour Doppler Ultrasound of the liver;body mass index (BMI);waist circumference;IL-1ß;IL-18;lipopolysaccharide (LPS);IL-6; | — |
Countries
China
Contacts
Public ContactHuilian Hua
Taizhou People’s Hospital
Outcome results
None listed