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A retrospective analysis of pathological response and prognosis following neoadjuvant immunotherapy in locally advanced head and neck squamous cell carcinoma

Correlation analysis between pathological response and prognosis following neoadjuvant immunotherapy in locally advanced head and neck squamous cell carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093179
Enrollment
Unknown
Registered
2024-11-29
Start date
2024-11-30
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Locally advanced head and neck squamous cell carcinoma (LA-HNSCC)

Interventions

Observation group:none

Sponsors

Sun Yat-sen Memorial Hospital, Sun Yat-sen University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients initially diagnosed with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) with complete medical records, laboratory results, and examination data. 2. All patients were pathologically confirmed to have squamous cell carcinoma. 3. All patients underwent neoadjuvant immunotherapy combined with chemotherapy followed by radical tumor resection. 4. Complete follow-up data is available for all patients.

Exclusion criteria

Exclusion criteria: 1. Patients who did not complete the standard treatment of neoadjuvant immunotherapy combined with chemotherapy and surgery. 2. Patients initially diagnosed with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). 3. Patients participating in other clinical trial studies. 4. Patients with concurrent other malignant tumors. 5. Patients with incomplete follow-up data.

Design outcomes

Primary

MeasureTime frame
%RVT;EFS;—

Secondary

MeasureTime frame
OS;RFS;—

Countries

China

Contacts

Public ContactXie Shule

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

xieshuleah@163.com+86 156 9243 4749

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026