Chronic Post-thoracotomy Pain
Conditions
Interventions
Test group:The test group was treated with oral celecoxib capsule 0.2 g, Q12 h in combination with Lidocaine Cataplasms
Control group:Patients in the control group were given oral celecoxib capsule 0.2 g, Q12 h
Sponsors
NanJing First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1)Age greater than or equal to 18 years, less than 80 years, gender-neutral; 2)Grade A healing of surgical incisions; 3)Pain is mainly confined to the peri-incision area, with NRS >= 4 at 1 week postoperatively; 4)Those whose cause of pain is primarily somatic rather than psychosomatic; 5)Expected survival >= 3 months.
Exclusion criteria
Exclusion criteria: 1) Allergy to nonsteroidal, amide local anesthetics or skin hypersensitivity to lidocaine patches; 2) History of continuous use of analgesic medication for 2 weeks prior to surgery; 3) Presence of pain other than incisional pain and need for analgesic medication other than the study medications; 4) The patient has a history of severe hepatic or renal function, cardiac insufficiency, gastrointestinal disorders such as creatinine >= 2 times the high limit of normal or ALT or AST >= 2.5 times the high limit of normal, Child C grade of hepatic function, or gastrointestinal perforation or obstruction; 5) Subject has a history of alcohol abuse, drug abuse; 6) Presence of depression and anxiety, inability to communicate verbally; cognitive deficits or mental illness; or other causes of impaired consciousness; 7) Patients who are unable to follow the study plan and visit schedule; 8) Participation in other clinical trials within 3 months prior to trial; 9) Pregnant and lactating women; 10) Those who, in the opinion of the researcher, cannot be enrolled for any reason whatsoever.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| numerical rating scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Douleurneuropathique 4 questions;daily sleep interference score;Analgesic drug use; | — |
Countries
China
Contacts
Public ContactXu Chenjie
Nanjing First Hospital
Outcome results
None listed