AECOPD
Conditions
Interventions
High flow nasal therapy:None
non-invasive ventilation:None
Nasal cannula:None
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients clinically diagnosed as AECOPD upon admission, along with respiratory failure, intubation withdrawal plan, or stable disease with NIV treatment
Exclusion criteria
Exclusion criteria: 1) Severe pneumonia, accompanied by pulmonary infiltration affecting more than 2 lung segments or 1 lobe of the lung. 2) coma patients 3) Recent upper respiratory tract surgery or facial trauma 4) Severe Obstructive Sleep Apnea Syndrome 5) Severe arrhythmias or acute coronary syndrome 6) Cardiac arrest with respiration cessation, weak autonomous breathing, paradoxical respiration, or hemodynamic instability due to respiratory failure, or other patients who require urgent tracheal intubation and invasive mechanical ventilation. 7) Severe Type I respiratory failure (PaO2/FiO2 < 100 mmHg) or severe ventilatory dysfunction (pH < 7.30) 8) Poor airway protection capability, with a high risk of aspiration. 9) Severe nasal congestion 10) Patients who refuse to participate in the study or in other research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| oxygenation index;PaCO2;mortality;Symptom and clinical score imrpovement;Total hospital cost;Hospital cost per day;Cost of ventilation or oxygen support; | — |
Countries
China
Contacts
Public ContactGuochao Shi
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed