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The clinical and pathological efficacy analysis of neoadjuvant therapy for lung cancer

The clinical and pathological efficacy analysis of neoadjuvant therapy for lung cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093155
Enrollment
Unknown
Registered
2024-11-29
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Chemotherapy group :
Chemo-immunotherapy group:chemo-immunotherapy

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosed with non-small cell lung cancer (NSCLC) through imaging and cytological examinations, with staging of II-III; 2.Pre-treatment pulmonary function FEV1 > 1.5 L; 3.Underwent neoadjuvant therapy (chemotherapy, chemo-immunotherapy, or targeted therapy) before surgery and received surgical treatment in our department (including pneumonectomy, lobectomy, and sublobar resection, along with mediastinal lymph node dissection); 4.No previous history of radiotherapy or chemotherapy.

Exclusion criteria

Exclusion criteria: 1.Combined with malignancies in other locations; 2.Liver, kidney, or heart dysfunction; 3.Presence of surgical contraindications; 4.Recurrence of non-small cell lung cancer; 5.Exploratory surgery as the surgical method; 6.Expected survival time <= 3 months.

Design outcomes

Primary

MeasureTime frame
Pathological remission rate;

Secondary

MeasureTime frame
Progression-free survival,PFS;Overall survival,OS;Objective Response Rate, ORR;

Countries

China

Contacts

Public ContactXie Jianlong

Affiliated Hospital of Guangdong Medical University

jlxiewy@gdmu.edu.cn+86 759 2387475

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026