coronary heart disease (CHD),type 2 diabetes mellitus (T2DM)
Conditions
Interventions
SGLT2i group:Patients who chose to receive SGLT2i treatment made their decision based on personal circumstances, health preferences, economic conditions, or their understanding of treatment risks.
Control group:Patients who, based on personal circumstances, health preferences, economic conditions, or their understanding of treatment risks, chose not to receive SGLT2i treatment.
Sponsors
Shijiazhuang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Diagnosed with CHD (based on typical angina symptoms and coronary angiography and/or ECG results) and comorbid T2DM (according to WHO diagnostic criteria);Aged 18-90 years;No use of SGLT2i for at least one month prior to enrollment;Willing to participate in the study and having signed informed consent.
Exclusion criteria
Exclusion criteria: Patients with severe hepatic or renal insufficiency (ALT or AST >3 times the upper limit of normal, eGFR <30 mL/min/1.73 m²); Patients currently receiving or planning to receive other novel antidiabetic therapies (e.g., GLP-1 receptor agonists); Pregnant or breastfeeding women; Patients with malignancies, hematological diseases, or severe infections; Patients requiring long-term anticoagulation therapy (e.g., warfarin or heparin) that may interfere with the study results; Patients with a history of allergy to SGLT2i or other medications used in the study; Patients with mental disorders, cognitive impairment, or other factors that hinder participation in the study or adherence to the treatment protocol; Patients participating in other clinical trials; Patients with incomplete or missing data records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Activated Partial Thromboplastin Time;Antithrombin III;Prothrombin Time;Prothrombin Activity;International Normalized Ratio;Fibrinogen;Thrombin Time; | — |
Countries
China
Contacts
Public ContactXiaoyue Qin
Shijiazhuang People's Hospital
Outcome results
None listed