age-related macular degeneration
Conditions
Interventions
Sponsors
Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: a. The clinical diagnosis of patients diagnosed as AMD is based on visual acuity examination, fundus slit lamp examination, Oberger fundus photography, optical coherence tomography angiography (OCTA); b. Age from 50 to 90 years old, regardless of sex, all underwent macular OCTA 6*6mm examination; c. Macular OCTA 6*6mm image signal >= 7; d.The basic treatment of vitreous injection was performed for 3 times.
Exclusion criteria
Exclusion criteria: a. Ametropia = + 3.00 D; b. Macular OCTA imaging quality is poor due to opacity of refractive media or difficulty in fixation. If the image signal is less than 7; c. Patients with other chorioretinal diseases and fundus hemorrhage; d. Patients with neovascularization or neovascular glaucoma combined with anterior segment (including iris and chamber angle); e. The study eye has active ocular inflammation or there is evidence of infectious blepharitis, keratitis, scleritis or conjunctivitis in any eye.; f. A history of external injuries to the eye or any previous intraocular surgery other than cataract surgery; g. Previous photodynamic therapy, laser photocoagulation, vitreous cavity anti-VEGF therapy; h. Other patients that the researchers believe need to be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retinal pigment epithelial detachment; | — |
Secondary
| Measure | Time frame |
|---|---|
| subretinal hyperreflective material;best-corrected visual acuity;central subfield thickness;Sub-foveal choroidal thickness; | — |
Countries
China
Contacts
Public ContactJie Zhong
Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital
Outcome results
None listed