postoperative analgesia
Conditions
Interventions
Standard sufentanil group:sufentanil PCIA
0 mg/h of oliceridine :Oliceridine PCIA, 0 mg/h
0.2 mg/h of oliceridine :Oliceridine PCIA, 0.2 mg/h
0.4 mg/h of oliceridine :Oliceridine PCIA, 0.4 mg/h
Sponsors
Affiliated Cancer Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients undergoing orthopedic surgery under elective general anesthesia; (2) Age: 18-68 years old; (3) ASA grades I-II; (4) BMI:18-30kg/m2.
Exclusion criteria
Exclusion criteria: (1) There were already other acute and chronic pains before the surgery; (2) Pregnancy, lactation, or planned pregnancy; (3) Suffering from mental and neurological disorders, chronic obstructive pulmonary disease or pulmonary heart disease, cardiovascular disease, etc; (4) Allergies or contraindications to anesthetics, adjunctive analgesics, salvage analgesics, antiemetic drugs, antibiotics used in the study; (5) Long term treatment with opioid drugs or use of any analgesic within 48 hours prior to surgery; (6) Suffering from sleep apnea syndrome; (7) For patients with contraindications to the investigational drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| patient satisfaction after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| analgesic condition;sedation condition;usage condition of analgesia pumps;adverse reactions; | — |
Countries
China
Contacts
Public ContactSun Yalin
Affiliated Cancer Hospital of Zhengzhou University
Outcome results
None listed