postpartum depression
Conditions
Interventions
experimental group:Single epidural injection of 0.25mg/kg 1mg/ml esketamine
control group:epidural injection of the same amount of normal saline
Sponsors
Yancheng First People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1: Pregnant women with full-term pregnancy between18 years old and 35 years old 2: No contraindication of spinal anesthesia 3: Sign informed consent form 4: ASA II 5: Able to complete scale survey independently 6: BMI<35kg/m2;
Exclusion criteria
Exclusion criteria: 1: A clear history of mental illness or communication problems 2: Serious pregnancy complications present before surgery 3: Contraindications to the use of ketamine/esketamine exist 4: Refuse to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence of PPD assessed by the Edinburgh Postnatal Depression Scale (EPDS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical Rating Scale for Pain(nrs);Postoperative sleep disturbances occurrence;Objective Sleep Duration;Apgar score of newborn;Effective pressing times of analgesic pump;Edinburgh Postnatal Depression Scale Score; | — |
Countries
China
Contacts
Public ContactLi Feng
Yancheng First People's Hospital
Outcome results
None listed