Post-stroke depression(PSD)
Conditions
Interventions
Non-depression after stroke:None
Mild depression after stroke:None
Moderate depression after stroke:None
Sponsors
Wenzhou Hospital of Traditional Chinese Medicine Affiliated of Zhejiang University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Meets defined diagnostic criteria for post-stroke depression, age between 18-70 years old, male and female; 2.stroke duration of 1-12 months; 3. Initial depression, HAMD-17 score = 8 points; 4.Patients with stable vital signs, clear consciousness, able to carry out basic communication and co-operate in completing the scale assessment; 5. Willing to cooperate with the whole trial process and sign the relevant informed consent form; 6.Right sharp hand.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the diagnostic criteria for post-stroke depression and are younger than 18 years old or older than 70 years old; 2. Those who have a history of mental illness caused by other reasons before the occurrence of stroke, or those who have suicidal tendency;3.Those who had depression for more than half a year; 4.Those who have a history of taking anti-anxiety and depression drugs within 2 weeks before enrolment; 5.Patients with severe systemic disorders, unstable vital signs, or severe heart, liver, kidney and other important organ failure;6. Those with impaired consciousness, severe aphasia, and severe cognitive impairment (MMSE = 9 points), which affects communication; 7.Those who are intolerant to antidepressant drugs (e.g., with prolonged QT interval, or congenital QT syndrome) or allergic; 8.Patients with unstable epilepsy control;9. Pregnant and lactating women; 10.Those who are not willing to co-operate to complete the follow-up of this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prefrontal cortex oximetry;Hamilton Depression Scale (17-item) scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-Depression Scale (SDS) scores; | — |
Countries
China
Contacts
Public ContactZhi Yinghao
Wenzhou Hospital of Traditional Chinese Medicine Affiliated of Zhejiang University of Traditional Chinese Medicine
Outcome results
None listed