Skull base-joint defect
Conditions
Interventions
experimental group:Combined skull base-TMJ prosthesis
Sponsors
Shanghai Ninth Peoples’ Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) The subjects were over 20 years old (inclusive), regardless of gender; 2) lesions causing skull base-joint defects; 3) those who did not participate in other clinical verification within 3 months; 4) no acute infectious disease, psychosis, or systemic disease; 5) Voluntary subjects and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) patients allergic to titanium implants; 2) patients with acute or severe infection or acute exacerbation of chronic infection; 3) patients with extensive soft tissue defects caused by surgery and insufficient soft tissue coverage of the wound after surgery; 4) patients with radiation osteomyelitis, acute and chronic osteomyelitis, osteoporosis; 5) patients with uncontrolled primary diseases of important organs such as heart, lung, brain and kidney; 6) patients with mental illness; 7) pregnant and lactating women; 8) patients unable to cooperate with treatment; 9) patients with advanced malignant tumors, distant metastasis or tumor recurrence; 10) critically ill patients, and it is difficult to make a definite evaluation of the effectiveness and safety of the prosthesis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QOL score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain;Maximum mouth opening;Function;Movement of the jaw;The osseointegration of the prosthesis;Maxillofacial morphology;Lateral movement; | — |
Countries
China
Contacts
Public ContactYang Chi
Ninth People's Hospital Affiliated to Shanghai JiaoTong University School of Medicine
Outcome results
None listed