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A comparative study of the effects of oxycodone and sufentanil polymodal analgesia on postoperative rehabilitation in patients undergoing thoracic surgery

A comparative study of the effects of oxycodone and sufentanil polymodal analgesia on postoperative rehabilitation in patients undergoing thoracic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093059
Enrollment
Unknown
Registered
2024-11-27
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung tumor

Interventions

oxycodone group:oxycodone 0.1mg/kg was given intravenously before skin incision
PCIA was applied to all patients for postoperative pain relief receiv- ing PCIA containing oxycodone 0.5 mg/ml (group O), hydromorphone 0.05 mg/ml (group H) or sufentanil 0.5 µg/ml (group S) combined
sufentanil group:sufentanil 0.1ug/kg was given intravenously before skin incision
PCIA was applied to all patients for postoperative pain relief and received PCIA containing sufentanil 40ug, combined with tropisetron 5 mg in 100 ml normal saline.The PCIA was set to deliver 5 ml bol

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.age 18 years or older, ; 2.elective thoracoscopic lung surgery. 3.American Society of Anesthesiolo- gists statuses I-III; 4.Voluntary signed informed consent form.

Exclusion criteria

Exclusion criteria: 1. Expected length of hospital stay was <48h; 2. Expected to enter the ICU after surgery; 3. Expected to bring an endotracheal tube back to the ward after surgery; 4. Patients with pregnancy or lactation; 5 .Known allergies to oxycodone and its adjuvants.

Design outcomes

Primary

MeasureTime frame
satisfactory analgesia with minimal emesis;The incidence of postoperative rebound pain;

Secondary

MeasureTime frame
Operation time;anesthesia time;blood loss;total amount of general anesthesia drugs;number of rescue analgesia and dosage;total number of PCIA presses and dosage;NRS scores at all time points of rest and cough 2h, 6h, 12h, 24h, 36h, 48h and 72h after surgery;PONV score for nausea and vomiting within 48h after surgery;QoR-15 score 24h, 48h, 120h after surgery and before discharge;Restore intestinal exhaust time;Restore drinking time;Restore eating time;Restore activity time;Drainage tube model, diameter, insertion depth, and removal time;stay time;intraoperative and recovery period complications from anesthesia;chronic pain;QoR-15 scores ;new disease after discharge;other complications after hospital discharge;

Countries

China

Contacts

Public ContactChen Changlin

Affiliated Hospital of North Sichuan Medical College

171575464@qq.com+86 135 5168 1936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026