None
Conditions
Interventions
Experimental group:Double-lumen endotracheal intubation
Control group:Single-lumen endotracheal intubation
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: For patients who are expected to require prolonged mechanical ventilation (such as critically ill patients, those in the postoperative recovery period, or those with traumatic brain injury, etc.), with an anticipated intubation duration greater than 4 days (5 days), aged 18-80 years; with no history of airway surgery, severe pulmonary infections, airway hyperreactivity, emphysema, bronchiectasis, or other related conditions. Patients must consent to participate in this study.
Exclusion criteria
Exclusion criteria: Airway Abnormalities: Patients with airway obstruction, laryngeal tumors, congenital airway abnormalities, etc. Severe Cardiopulmonary Insufficiency: Patients who cannot tolerate double-lumen endotracheal intubation, such as those with cardiogenic shock or severe acute respiratory failure. Pregnant Women: Due to safety concerns, pregnant women are typically excluded from such studies. Allergic History: Patients with a history of allergy to endotracheal intubation or anesthetic drugs. Others: Such as patients with active infections or contraindications to the study drugs or treatments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tracheal cuff pressure-induced injury to the airway wall; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of ventilator-associated pneumonia;Incidence of airway reactions;Phlegm and secretion volume;Whether the airbag leaks or not;Amount of suction on the sac; | — |
Countries
China
Contacts
Public ContactHongsheng Ji
Shandong Provincial Hospital
Outcome results
None listed