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A clinical study of a diagnostic prediction model for cognitive impairment after acute large vessel occlusive stroke

A clinical study of a diagnostic prediction model for cognitive impairment after acute large vessel occlusive stroke

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093035
Enrollment
Unknown
Registered
2024-11-27
Start date
2024-03-18
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Interventions

Divided into cognitive impairment group (PSCI group) and non cognitive impairment group (PSCI group) through neuropsychological assessment:NA

Sponsors

Ya 'an People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Patient aged 18-80 years (2) Clinically first confirmed acute ischemic large vessel occlusive stroke (confirmed by CTA, MRA or DSA, stroke can be attributed to 50-99% stenosis or occlusion of intracranial large arteries); (3) Ability to perform neuropsychological assessment (MMSE, MoCA, IQCODE, or LOTCA, etc.) (4) Patients or family members who sign an informed consent form and are able to cooperate with the examination and complete the study; Note: If any of the above answers are "No", this subject cannot participate in the validation

Exclusion criteria

Exclusion criteria: (1) 1. Age25 at admission or mRS> within 14 days of admission2 points) or/and other imaging evidenced by severe stroke; (7) Intracranial hemorrhagic disorders: hemorrhagic stroke, epidural hematoma, subdural hematoma, ventricular hemorrhage or subarachnoid hemorrhage; (8) Intracranial aneurysm, arteriovenous malformation; (9) Patients with severe systemic diseases or multi-organ failure, hematologic diseases, connective tissue diseases, endocrine and metabolic diseases (except well-controlled diabetes); (10) Infected patients with malignant tumors and life expectancy at the time of selection; (11) Pregnant or lactating females; (12) Serious diseases of important organs such as heart, liver, kidneys, and lungs; (13) Those who cannot lie quietly for 20 minutes or have claustrophobia; (14) Highly sensitive to X-rays or should not be exposed to X-rays (such as aplastic anemia, etc.); (15) Previous allergy to tracer or other drugs; (16) Hachin ski Ischemia Index Scale<4; (17) Other conditions that the investigator believes may have an impact on the results of this study Note: If any of the above answers are "yes", this subject cannot participate in the validation

Design outcomes

Primary

MeasureTime frame
Mini-Mental State Examination;Montreal Cognitive Assessment;

Secondary

MeasureTime frame
Modified Rankin Scale;

Countries

China

Contacts

Public ContactJian Wang

Ya 'an People's Hospital

wangjian0724@126.com+86 135 5006 4528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026