critically ill children
Conditions
Interventions
Observation group:None
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: ? Infants admitted to NICU and PICU from January 1, 2018, to March 31, 2023; ? Age <18 years, any gender; ? Patients admitted and underwent routine blood tests using Mindray Medical's five-classification blood cell analyzer (including BC6000, BC6000PLUS, BC6800PLUS, BC7500 series), with the instrument or computer system retaining relatively complete multimodal blood cell data; ? Accessible and detailed clinical medical records relevant to this study; ? For patients readmitted to NICU or PICU multiple times, each readmission is considered as a new case due to varying conditions, etiology, and outcomes.
Exclusion criteria
Exclusion criteria: 1. Cardiac arrest or death within 24 hours of admission; 2. Children with blood diseases, including iron deficiency anemia, megaloblastic anemia, hereditary spherocytosis, erythrocyte glucose-6-phosphate dehydrogenase deficiency, thalassemia, autoimmune hemolytic anemia, aplastic anemia, immune thrombocytopenia, acute lymphoblastic leukemia, acute non-lymphocytic leukemia, multiple myeloma, Henoch-Schonlein purpura, myelodysplastic syndrome, etc.; 3. Children with hereditary metabolic diseases, including galactosemia, mucopolysaccharidosis, glycogen storage disease, phenylketonuria, albinism, melaturia, hypoxanthine-guanine phosphoribosyltransferase deficiency, xeroderma pigmentosum, Gaucher disease, Tay-Sachs disease, etc.; 4. Children with chromosomal diseases, including Down syndrome, trisomy 18, etc.; 5. Children with congenital immunodeficiency diseases; 6. Children transfused with blood products within half a year, including transfusion of component blood, human immunoglobulin, etc.; 7. Children with a hospital stay of < 24 hours; 8. Non-critically ill children who are temporarily transitioning to the NICU or PICU due to bed problems in other wards.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| death;sepsis; | — |
Secondary
| Measure | Time frame |
|---|---|
| MODS;DIC;chronic lung disease or acute respiratory distress syndrome in children;shock;time of death;PICU or NICU hospitalization duration;Brain injury or neurological complications; | — |
Countries
China
Contacts
Public ContactHe yan
Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University
Outcome results
None listed