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Comparative study on analgesic effect of dexmedetomidine combined with butorphanol after posterior spinal surgery

Comparative study on analgesic effect of dexmedetomidine combined with butorphanol after posterior spinal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093015
Enrollment
Unknown
Registered
2024-11-27
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain due to posterior spinal approach surgery

Interventions

Dexmedetomidine plus Butorphanol:dexmedetomidine 0.1 µg/kg/h plus butorphanol 0.125 mg/kg
Butorphanol Group:given butorphanol 0.125 mg/kg in analgesic pump

Sponsors

Zigong Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 58 Years

Inclusion criteria

Inclusion criteria: 1.25 years old = age = 58 years old; 2.Patients who conform to ASA Classification I-II; 3.18 kg/m2 = BMI < 28 kg/m2;

Exclusion criteria

Exclusion criteria: 1.Patients with hypertension or ischemic heart disease; 2.Patients who had taken ß-adrenoreceptor blockers, analgesics, or tranquilizers within one week prior to the study; 3.Patients with a history of postoperative nausea and vomiting; 4.Patients with neuropsychiatric diseases, conduction abnormalities,; 5.Allergies to butorphanol or dexmedetomidine.

Design outcomes

Primary

MeasureTime frame
Postoperative pain;

Secondary

MeasureTime frame
Sedation scoresafter surgery;Adverse reactions;Vital signs;Number of analgesic pump presses;Patient Satisfaction;

Countries

China

Contacts

Public ContactBoran Deng

Zigong Traditional Chinese Medicine Hospital

1468631587@qq.com+86 81 35101862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026