acute exacerbation of chronic obstructive pulmonary disease, AECOPD
Conditions
Interventions
Experimental group:In addition to receiving routine COPD treatment, use LITE equipment twice a day for 15-20 minutes each time. The use of LITE devices will be independently completed by participants
2. Guide the patient to inhale deeply to 3/4 of the maximum inspiratory volume or at least inhale harder than usual, hold for 2-3 seconds, and then continue to exhale slowly until the functional resid
3. Remove the device and cough "Huff" 2-3 times. One group in the morning and one group in the evening, with each group lasting 15-20 minutes, and intervention until the end of follow-up.
Control group:Conventional treatment
conventional therapy
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Meet the COPD diagnostic criteria of the 2024 Global Initiative for Chronic Obstructive Lung Disease (GOLD Guidelines), with a GOLD classification of 2-4, and meet the definition of acute exacerbation; 2.Age: 18-80 years old; Gender is not limited; 3.The frequency of expectoration is more than 5 times per day, and the duration of each expectoration is more than 30 seconds; 4.Able to understand and cooperate with the use of Lite devices 5.The patient or family member has a full understanding of the purpose and significance of this experiment, voluntarily participates in the study, and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women; 2.Respiratory active bleeding; 3.Mental disorders, unable to cooperate with the experimenter.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Forced vital capacity, FVC;Forced Expiratory Volume in the first second,FEV1;Peak expiratory flow ,PEF;White blood cell count;Neutrophil percentage;C-reactive protein;PaCO2;PaO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Medical Research Council,mMRC;Cough Assessment Tool; | — |
Countries
China
Contacts
Public ContactYugang Zhuang
Shanghai Tenth People's Hospital
Outcome results
None listed