Sudden Sensorineural Hearing Loss
Conditions
Interventions
SSNHL group:none
Healthy control group:none
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-60 years with a chief complaint of unilateral hearing loss lasting no more than 30 days, meeting the diagnostic criteria for sudden sensorineural hearing loss (SSNHL). 2.Healthy subjects aged 18-60 years, matched with the experimental group in terms of age and gender.
Exclusion criteria
Exclusion criteria: 1.Bilateral episodes. 2.Individuals with neurological or psychiatric disorders such as cognitive impairment, autism, epilepsy, depression, or acoustic neuroma. 3.Pregnant and breastfeeding women. 4.Patients with a history of allergy to glucocorticoids. 5.Those with a history of sudden hearing loss. 6.Individuals with claustrophobia. 7.Those with severe vertigo symptoms. 8.Patients whose cause of hearing loss has been confirmed by audiological and MRI examinations. 9.Individuals with other ENT conditions such as otitis media or otolithiasis. 10.Those with cardiovascular diseases, diabetes, liver or kidney dysfunction, tumors, coagulation disorders, autoimmune diseases, syphilis, or HIV/AIDS. 11.Individuals unwilling to cooperate with follow-up visits at the hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| phase lag index;degree;Betweenness Centrality;Eccentricity;Diameter;Leaf Fraction;Tree Hierarchy;Mean Eccentricity;Gray matter volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| hearing threshold;ACT;Mandarin Hearing In Noise Test;self-rating anxiety scale;self-rating depression scale;tinnitus handicap inventory;dizziness handicap inventory; | — |
Countries
China
Contacts
Public ContactHaotian Liu
West China hospital, Sichuan University
Outcome results
None listed