Shivering
Conditions
Interventions
Combined group:Esketamine combined with dexmedetomidine
dexmedetomidine group:Dexmedetomidine by intravenous pump
Blank group:Normal saline is injected intravenously and pumped
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) ASA classification ?-?; (2) Age 18-80 years old (3) Body mass index ( BMI) 18-30kg/m2; (4) Estimated operation time 1-3h.; (5) Informed consent signed by the patient and family members
Exclusion criteria
Exclusion criteria: (1) history of allergy related to anesthesia drugs in the study; (2) patients with severe bradycardia or arrhythmia, patients taking adrenergic receptor antagonists; (3) hyperthyroidism, hypothyroidism; (4) hypertension grade III, cardiac function class III and above; (5) refusal to cooperate or relevant mental disorders; (6) intraoperative bleeding >1000 ml; (7) patients with admission body temperature higher than 38.0? or lower than 36.0?; (8) patients with contraindications to intrathecal anesthesia or puncture failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| shivering;body temperature; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypertension;pulse rate;Ramsay Sedation Scale;CRBD score;Pulse oximetry;quality of recovery-40 questionnaire; | — |
Countries
China
Contacts
Public ContactLin Lanying
Department of Anesthesiology, the First Affiliated Hospital of Fujian Medical University
Outcome results
None listed