acute radiation-induced esophagitis
Conditions
Interventions
Test group:Esophagitis prescription was given 2ml tid orally.Generally, the drug was given 5 days a week and rested for 2 days for 4 consecutive weeks, followed up for 1 month.
Control group:The control group was given Lining glue 10pm 3G tid+ sucralfate 10ml tid+ fluconazole 200mg QD orally.usually given 5 days a week for 2 days rest for 4 weeks, and were followed up for 1
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) 18-75 years old; 2) Lung / esophageal cancer patients with radiotherapy indications; 3) ECOG score 0-1; 4) ability to drink water or take oral Chinese medicine granules; 5) expect to survive more than 48 weeks; 6) voluntarily and sign informed consent
Exclusion criteria
Exclusion criteria: 1) esophageal stenting has been performed. 2) when the patients were enrolled in the study, they could not eat at all. Unable to swallow or take oral test drugs. 3) pregnant and lactating women. 4) known or suspected to be allergic to tested drugs or to any drug given in connection with this trial. 5) Drug abuse and medical, psychological or social conditions may interfere with patients' participation in the study or affect the evaluation of the results of the study. 6) patients who the researchers believe are not suitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain disappearance time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety index;Curative effect index;Esophagography;Nutritional status;Psychological evaluation;Taste evaluation; | — |
Countries
China
Contacts
Public ContactBaoguo Sun
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed