A Prospective Study on the Attainment Rate, Influencing Factors, and Prognosis of Initial Vancomycin Trough Concentrations in the Treatment of Sepsis Due to Gram-Positive Bacterial Infections

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400092966

Enrollment

Unknown

Registered

2024-11-26

Start date

2024-12-01

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Observation group:None

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients admitting to the intensive care unit of our hospital; 2. Aged >= 18 years; 3. Met the Sepsis3.0 diagnostic criteria for sepsis; 4. Patients Treated with Vancomycin for Antibacterial Therapy with Therapeutic Drug Monitoring; 5. Voluntarily participated in this study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to participate in this study; 2. Patients receiving palliative care or those who discharge against medical advice; 3. Patients with vancomycin treatment duration of less than 48 hours; 4. Patients without the detection of Gram-positive bacteria in microbiological tests.

Design outcomes

Primary

Measure	Time frame
Attainment Rate of Initial Vancomycin Trough Concentration;30-day mortality rate;	—

Countries

China

Contacts

Public ContactXuemeng Xie

Affiliated Hospital of Jining Medical University

756252748@qq.com+86 155 8732 1325

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026