Changxin Guan Mild Cognitive Impairment
Conditions
Interventions
acupuncture group:acupuncture treatment
waiting group:Brief health education and no other interventions.
Sponsors
Shenzhen Baoan District People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with mild cognitive impairment and older adults with relatively normal cognition are eligible: ? 3 months after infection with the new coronavirus; ? aged 60-75 years; ? with secondary school education or above; ? those who have been certified as healthy by a physical examination at a tertiary hospital within the last six months. Age 60-75 years old; (3) Secondary school education or above; (4) Physical examination at a hospital of tertiary level or above within the last six months to prove that they are in good health; ? Body mass index (BMI) within the range of 20-24; ? All are right-handed; ? Signed informed consent. Patients with Changxin Guan Mild Cognitive Impairment also meet the diagnostic criteria of MCI (refer to 2018 China Dementia and Cognitive Impairment Diagnosis and Treatment Guidelines). The patients with mild cognitive impairment also met the diagnostic criteria for MCI (referring to the 2003 International Working Group diagnostic criteria for MCI recommended by the 2018 China Dementia and Cognitive Impairment Diagnostic and Treatment Guidelines) and the World Health Organization's diagnostic criteria for Changxincuan;
Exclusion criteria
Exclusion criteria: ? metal residues in the body, tattoos and other unsuitable for magnetic resonance examination; ? fear of MRI or other reasons can not be MRI scanners; ? found that there are obvious lesions in the brain or suspected foci; ? large amounts of alcohol, drug abuse; ? history of mental illness or congenital mental developmental delays; in the last three months or are taking psychotropic drugs such as anti-anxiety or antidepressant medications, patients undergoing psychological treatment, or Use of drugs and treatments that have obvious effects on cognition; (6) People with serious heart, liver, kidney diseases, brain tumors, encephalitis, epilepsy, Parkinson's disease and other neurological diseases that can cause cognitive dysfunction. ? metal residues in the body, tattoos and other inappropriate for magnetic resonance examination; ? fear of MRI or other reasons can not be MRI scanners; ? found that there are obvious foci or suspected foci of the brain; ? large amounts of alcohol, drug abuse; ? history of mental illness or congenital mental developmental delays; within the last three months or are taking anti-anxiety or antidepressant drugs such as psychotropic drugs, psychotherapeutic patients, or use of cognitively significant impact of the medications and treatments; ? accompanied by severe cardiac, hepatic, renal diseases, brain tumors, brain encephalitis, epilepsy, Parkinson's disease, and other neurological diseases that can lead to cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MOCA scale;Resting-state fMRI data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Dementia Scale;Simple Mental Status Examination Scale;auditory verbal learning test-huashan version; | — |
Countries
China
Contacts
Public ContactShangjie Chen
Shenzhen Bao'an District People's Hospital
Outcome results
None listed