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Research on the Brain Mechanism of Individualized TMS Intervention on the Reward Network of Autism Spectrum Disorder

Research on the Brain Mechanism of Individualized TMS Intervention on the Reward Network of Autism Spectrum Disorder

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092959
Enrollment
Unknown
Registered
2024-11-26
Start date
2024-11-26
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Interventions

Precision positioning group:Using the right NAc coordinate point as the origin and a radius of 5mm, generate a spherical Region of Interest (ROI) for one NAc, and use functional connectivity to find t
Classic positioning group:Using the classic "5cm" positioning method to determine the right stimulation target

Sponsors

Hangzhou Normal University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age over 3 years old; 2. Meets the diagnostic criteria for autism in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) in the United States; 3. CARS scale scores > 30 points.

Exclusion criteria

Exclusion criteria: Trisomy 21 syndrome; Schizophrenia; Hearing impairment; History of febrile seizures and epileptic seizures; History of traumatic brain injury, cranial infection, brain tumor, etc; History of metal implantation in the skull or intracranial surgery; History of taking antipsychotic or antiepileptic drugs.

Design outcomes

Primary

MeasureTime frame
Functional connectivity;perAF;ReHo;

Secondary

MeasureTime frame
Childhood Autism Rating Scale Score;Social Responsiveness Scale Score;Repetitive Behavior Scale-Revised Score;Strength and Difficulties Questionnaire Score;Reading the mind in the eyes test score;

Countries

China

Contacts

Public ContactYufeng Zang

Hangzhou Normal University; Hangzhou Normal University Affiliated Hospital

zangyf@hznu.edu.cn+86 186 0651 7380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026