Stroke
Conditions
Interventions
Health group(HP):For 5 consecutive days, once/day, 20 minutes/time, brain-computer interface training
Stroke Attention-impaired Group (SOAD):For 5 consecutive days, once/day, 20 minutes/time, brain-computer interface training
Stroke Attention Disorder Group (SWAD):For 5 consecutive days, once/day, 20 minutes/time, brain-computer interface training
Healthy DLPFC group(HDLPFC):For 5 consecutive days, once a day, 10HZ rTMS (20min DLPFC as the target) + brain-computer interface training (20min)
Stroke DLPFC group(SDLPFC):For 5 consecutive days, once a day, 10HZ rTMS (20min DLPFC as the target) + brain-computer interface training (20min)
Health fake stimulation group(HFG):For 5 consecutive days, once a day, 10HZ rTMS (20min fake stimulation) + brain-computer interface training (20min)
Stroke fake stimulation group(SFG):For 5 consecutive days, once a day, 10HZ rTMS (20min fake stimulation) + brain-computer interface training (20min)
Sponsors
The Fifth Affiliated Hospital of Guangzh Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Part I: Inclusion criteria of healthy subjects: (1) Aged 18-75 years, including 18 and 75 years; (2) limbs sound, no motor dysfunction: (3)MMSE>=27 points: voluntarily sign the informed consent. Inclusion criteria: (1) Stroke patients diagnosed in accordance with the diagnosis of cerebrovascular diseases in the Chinese Classification of Cerebrovascular Diseases 2019; (2) Cerebral stroke confirmed by CT or MRI; (3) Cerebral apoplexy resulting in one upper limb dysfunction, Burunnstrom hand stage 1-5: (4) age 18-75 years old, including 18 and 75 years old; Simple mental State Examination Scale (MMSE) 6 years; (3) No obvious impairment of vision and hearing; (4) The score of the simple mental State Examination Scale (MMSE) is >=27 points; (5) The Edinburgh Handedness Inventory was right-handed; (6) Agree to participate and sign informed consent. Stroke inclusion criteria: (1) Stroke patients diagnosed with cerebrovascular diseases in accordance with the diagnostic points of Chinese Classification of Cerebrovascular Diseases 2019; (2) Cerebral stroke confirmed by CT or MRI; (3) Cerebral apoplexy resulting in one upper limb dysfunction, Burunnstrom hand stage 1-5: (4) age 18-75 years old, including 18 and 75 years old; Simple mental State Examination Scale (MMSE) <27 points, can understand and cooperate with the completion of the experiment; (5) Edinburgh Handedness Scale was assessed as right-handedness; (6)Voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with previous brain-related diseases affecting cognitive function; 2. There are previous diseases that affect exercise ability, such as fracture history, brain injury history, limb pain, etc.; 3. suffering from serious mental disorders; 4. Taking drugs that affect cognitive function; 5. Patients with serious heart, lung, liver, kidney or other system diseases, malignant tumors and epilepsy; 6. Those who do not cooperate to complete the assessment; 7. Pregnancy, need to improve pregnancy examination; 8. Any implanted device or metal may be affected by magnetic fields generated by transfrequency magnetic stimulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxy-hemoglobin,HbO; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bci response rate;n-back normal form correct rate;n-back paradigm response time; | — |
Countries
China
Contacts
Public ContactHaining Ou\Zirui Luo
Guangdong Hospital of Traditional Chinese Medicine\The Fifth Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed