The most common early clinical manifestations of diabetic retinopathy include microaneurysm formation and intraretinal hemorrhage. Microvascular injury results in retinal capillary nonperfusion, cotton-wool spots, increased number of hemorrhaged, venous abnormalities, and intraretinal microvascular abnormalities (IRMA). At this stage, increased vascular permeability leads to retinal thickening (ed
Conditions
Interventions
T1DM patients Group:Social determinants of health
T2DM patients Group:Social determinants of health
Sponsors
Tianjin Medical University Eye Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 20 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with diabetes in Tianjin Medical University Chu Hsien-I Memorial Hospital; 2.(2) Under 20 years old; 3.(3) Clear consciousness, no mental disease, accessible to communicate; 4.(4) Agree to participate in the study and be able to attend the follow-up on time;
Exclusion criteria
Exclusion criteria: 1. Unwilling or unable to consent to participate in the study, participate in a follow-up visit on time, or return for a scheduled protocol visit; 2.(2) Participated in another clinical trial within 3 months; 3.(3) Patients with severe cardiopulmonary function damage, liver and kidney function damage, and advanced cancer; 4.(4) Patients with severe mental illness;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-mydriatic fundus photography;Visual acuity;Optical coherence tomography and optical coherence tomography angiography (OCTA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Optical biometry;Intraocular pressure;Medical measurement;Fasting blood glucose;Questionnaire survey;Glycosylated hemoglobin;Urine ACR;blood triglyceride;urine creatinine;blood cholesterol; | — |
Countries
China
Contacts
Public ContactLiu Juping
Tianjin Medical University Eye Hospital
Outcome results
None listed