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Multicenter Real-World Cohort Study of Lorlatinib for Treatment-Related Hyperlipidemia

Multicenter Real-World Cohort Study of Lorlatinib for ALK-Positive Advanced Non-Small Cell Lung Cancer-Associated Hyperlipidemia

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092915
Enrollment
Unknown
Registered
2024-11-26
Start date
2024-11-28
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Observation group:None

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Advanced ALK+ NSCLC diagnosed by pathohistology and/or cytology This study is a real-world study and can be considered for inclusion in patients with advanced non-small cell lung cancer who have received lorlatinib as the initial or subsequent line of therapy and have detailed medical information. Patients with advanced ALK+ NSCLC confirmed by histopathological and/or cytological examination ECOG score 0-2 points Age 18 to 80 years old Take lorlatinib for at least 20 days Eligible for the first phase of the study subject exempt from informed consent, with information confidentiality instructions In the second stage, the study subjects need to sign the informed consent form, have good compliance, and cooperate with the follow-up

Exclusion criteria

Exclusion criteria: Treatment with other anti-cancer drugs during lorlatinib treatment

Design outcomes

Primary

MeasureTime frame
3m-concentrations;Hypersensitive C-reactive protein;IL-6;cIMT;Coronary calcification score;

Countries

China

Contacts

Public ContactLiang Li

Peking University Third Hospital

liangli_puth@126.com+86 10 8226 5857

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026