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The effect of bile reflux on the occurrence of inflammatory syndrome in patients with gastric diseases after ESD operation

The effect of bile reflux on the occurrence of inflammatory syndrome in patients with gastric diseases after ESD operation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092900
Enrollment
Unknown
Registered
2024-11-26
Start date
2024-11-27
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-ESD inflammatory syndrome

Interventions

none:none

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-90 years who received ESD surgery in our hospital due to gastric disease. ? Access to baseline information from electronic medical records: These included age, sex, history of antiplate/anticoagulant drug use, location of gastric lesions (fundus/cardia, body of stomach, Angle of stomach, antrum), lesion type (precancerous lesion/submucosal tumor/other), lesion size, lesion depth (mucosa, submucosa, muscularis lamina proper), overall resection rate, R0 resection rate, and so on. ESD operation time (defined as the time from the beginning of submucosal injection to the completion of submucosal dissection), wound management (closed/not closed), length of hospital stay (defined as the day of ESD surgery to the day of discharge) ? Endoscopic bile reflux images (Grade 0: clear mucous lake; Grade 1: Light yellow mucous lake; Grade 2: yellow-green slime lake; Grade 3: Dark yellow, thick, cloudy mucous lake with bile plaque obstruction)

Exclusion criteria

Exclusion criteria: (1) The patient had a history of gastrectomy or esophagectomy (2) Patients who underwent ESD on the same day due to other lesions (3) Patients with perforation or delayed perforation during ESD surgery (4) Patients who require further gastroscopy or surgery due to other ESD-related adverse events, including delayed bleeding (5) Patients who received antibiotics before or after ESD due to infectious diseases not related to ESD.

Design outcomes

Primary

MeasureTime frame
the occurrence of PEIS;

Countries

China

Contacts

Public ContactHui, Zhou

Shanghai General Hospital

mdzhouhui@163.com+86 130 3217 2900

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026