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Comparison of oliceridine and sufentanil for prophylactic analgesia in gynecologic laparoscopic surgery

Comparison of the efficacy of oliceridine versus sufentanil for preventive analgesia in gynecologic laparoscopic surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092891
Enrollment
Unknown
Registered
2024-11-26
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic tumor

Interventions

Sufentanil group :Administer 0.1 ug/kg of Sufentanil 5 minutes before incision and 10 minutes before the end of the surgery
Oliceridine group :Administer 0.02mg/kg of Oliceridine 5 minutes before incision and 10 minutes before the end of surgery

Sponsors

Cancer Hospital of Shantou University Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.With the approval of the hospital's ethics committee, adult female patients who have signed the informed consent form for anesthesia and the informed consent form for participating in the study are planned to undergo gynecological laparoscopic surgery with endotracheal intubation under general anesthesia; 2.Age between 18 to 65 years old, classified as ASA I to II, with a body mass index (BMI) ranging from 18 to 28 kg/m².

Exclusion criteria

Exclusion criteria: 1.Patients allergic to the study medication. 2.Patients with long-term use of opioid drugs. 3.Patients with severe liver and kidney dysfunction. 4.Patients with gastrointestinal obstruction, at risk of aspiration. 5.Patients with nausea and vomiting within 24 hours preoperatively or those who have used prophylactic antiemetic drugs.

Design outcomes

Primary

MeasureTime frame
Area under the curve of the VAS score;

Countries

China

Contacts

Public ContactXu Xiang

Cancer Hospital of Shantou University Medical College

xuxiang716@sina.cn+86 134 2533 0422

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026