oral submucous fibrosis(OSF)
Conditions
Interventions
Treated group:Triamcinolone acetate injection treatment, curcumin gel local application adjuvant treatment
Sponsors
Hunan Xiangya School of Stomatology, Central South University (Xiangya Stomatological Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Patients who either conform to the Diagnostic Criteria for Oral Submucosal Fibrosis (Full details are given in Appendix A) or have been pathologically diagnosed with OSF. (2) Individuals aged between 18 to 60 years. (3) Participants who have refrained from using immunomodulatory agents or hormonal medications for a period of three months prior to the study.
Exclusion criteria
Exclusion criteria: (1) Individuals with allergies to curcumin or any other gel components. (2) Patients suffering from malignant oral mucosa diseases, such as cancerous ulcers. (3) Pregnant and breastfeeding women. (4) Individuals with mental illnesses or cognitive impairments that may affect their ability to comply with the study protocol. (5) Patients who are unlikely to adhere to the medical advice or to attend follow-up appointments as scheduled. (6) Patients with other localized or systemic conditions that could interfere with the study outcomes or participant safety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interincisor distance;Scores of mucosal colors;Scores of mucosal textures; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain index of mucosa; | — |
Countries
China
Contacts
Public ContactWang Yuehong
Hunan Xiangya School of Stomatology, Central South University (Xiangya Stomatological Hospital)
Outcome results
None listed