Venous thrombotic disease
Conditions
Interventions
Rosuvastatin group:Rosuvastatin calcium tablets once daily for three months
Sponsors
Shanxi Bethune Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with first episode of deep venous thrombosis of lower extremity (with or without pulmonary embolism) (less than 3 months); 2. between the ages of 18 and 80; 3. Good organ function, including but not limited to: (1) Good liver function: AST/SGOT and/or ALT/SGPT 50 mL/min; (3) Good cardiopulmonary function; (5) Good bone marrow function: absolute neutrophil count (ANC) >=1.5×10^9/L, hemoglobin (Hb) >=80g/L, platelet (PLT) >=100×10^9/L; 4. Conservative treatment was assessed by a professional doctor or the patient and family members strongly wished during the treatment; 5. No surgical treatment was performed during the later follow-up. 6. Patients who did not lose follow-up and had incomplete data during the review. 7. Sign written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients younger than 18 years old or older than 80 years old with a life expectancy of less than 3 years; 2. Have taken or are taking statins; 3. Combination of arterial disease or use of anti-plate drugs (such as aspirin), cyclosporine, or other lipid-lowering treatment; 4. People who are allergic to statins; 5. Pregnancy and lactation; 6. There are strict contraindications for the use of statins; 7. Severe diseases of liver and kidney function; 8. Patients to be treated with surgery; 9. History of VTE or PTS; 10. Women who are pregnant or trying to become pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood cell analysis;Blood lipid;D-Dimer;Liver function;renal function;C-reactive protein;Villalta rating; | — |
Countries
China
Contacts
Public ContactTao Yang
Shanxi Bethune Hospital
Outcome results
None listed