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Application of multi-delay ASL perfusion imaging in population with cognitive impairment

Application of multi-delay ASL perfusion imaging in population with cognitive impairment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092880
Enrollment
Unknown
Registered
2024-11-25
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease (AD)

Interventions

Subjective Cognitive Decline (SCD):None
Mild Cognitive Impairment (MCI):None
Healthy Control (HC):None

Sponsors

Huai'an First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1.age range between 55-79; 2.right hand; 3.Education: Junior high school or above; 4.Mini-Mental State Examination Scale (MMSE) score > 24

Exclusion criteria

Exclusion criteria: 1.Other dementia-related neurodegenertaive diseases or depression, neuro-developmental abnormalities, mania, depression, neurophrenia, etc. within the 2 years; 2.Central nervous system diseases, including traumatic brain injury, intracranial hemorrhage, acute cerebral infarction, etc; 3.History of severe sinusitis, nasal cavity and sinus polyps, congenital diseases of the skull base and trauma; 4.Combined with serious damage to the function of heart, liver, kidney and other organs; 5.Contraindications to MRI examination, such as implantation of metal prostheses in the body, claustrophobia, wearing of an insulin pump

Design outcomes

Primary

MeasureTime frame
Cerebral blood flow (CBF);

Secondary

MeasureTime frame
Arterial transit time (ATT);

Countries

China

Contacts

Public ContactLili Guo

Huai'an First People's Hospital

guolili163@163.com+86 13651549848

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026