Chronic hepatitis B
Conditions
Interventions
Adjust the drug according to the response to the virus: medication adjustment therapy
Sponsors
Linyi People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-65 years old, gender unlimited; 2.Patients with HBV infection who meet the diagnostic criteria of the Chronic Hepatitis B Prevention and Treatment Guidelines (2022 edition); 3.HBV DNA can be detected; 4.Patients who agree to participate in this clinical trial and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients younger than 18 years old and older than 65 years old ; 2. Patients co-infected with human immunodeficiency virus or requiring long-term immunosuppressants ; 3. Patients who plan to receive organ transplantation or have received organ transplantation ; 4. Patients with liver cancer or other malignant tumors; 5. Patients with serious underlying diseases, including heart, brain, lung, digestive, blood, urinary, neuropsychiatric and other diseases; 6. Patients with other liver diseases, including viral hepatitis C, alcoholic hepatitis, drug hepatitis, autoimmune liver disease, etc. 7. Have a history of alcohol or drug abuse within the last 1 year; 8. Patients who have participated in clinical trials of other drugs within the last 3 months; 9. Patients with compensatory and decompensated cirrhosis and liver failure; 10. Patients with poor compliance, unable to adhere to or unwilling to participate in the study, or patients who are not suitable to participate in the clinical study according to other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT;HBV DNA;Biochemical tests; | — |
Secondary
| Measure | Time frame |
|---|---|
| hepatic imaging;Blood routine examination; | — |
Countries
China
Contacts
Public ContactXing Liu
Linyi People's Hospital
Outcome results
None listed