Septic cardiomyopathy
Conditions
Interventions
Patients with sepsis-induced cardiac dysfunction:None
Sponsors
The First Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Age>=18 years old; (2) Patients with sepsis or septic shock. Sepsis and septic shock are diagnosed according to the 2016 International Sepsis Guidelines sepsis3.0, which is defined as the presence or suspicion of infection, and the SOFA score rises above baseline by >=2 points. Septic shock is defined as maintenance of MAP =65 mmHg with vasoactive medication and a blood lactate level of > 2 mmol/L despite adequate fluid resuscitation on the basis of a clear diagnosis of sepsis. (3) Diagnosis of sepsis should not be carried out within 24 hours
Exclusion criteria
Exclusion criteria: 1. Ischemic cardiomyopathy, hypertrophic cardiomyopathy, dilated cardiomyopathy confirmed by echocardiography 2. Acute coronary syndrome or heart failure in recent 30 days 3. Moderate to severe valvular heart disease and after valve replacement 4. Pregnancy status 5. Chronic heart failure with reduced ejection fraction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global longitudinal strain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient 28 days survival; | — |
Countries
China
Contacts
Public ContactSi Xiang
The First Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed