Postoperative residual neurological symptoms of degenerative lumbar spinal stenosis
Conditions
Interventions
limaprost tablet group:Take limaprost tablets, 3 times a day, 5 µg/time
Celecoxib group:Take celecoxib capsules, once daily, 0.2 g/time
Sponsors
The Third Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patient or his/her guardian voluntarily participates in the study and signs informed consent, and can comply with the programme and the procedures of visits; 2. In our hospital for degenerative lumbar spinal stenosis in patients with single-level lumbar fusion surgery, patients discharged from the day (D10) to assess their postoperative residual pain; Or in the outside hospital because of degenerative lumbar spinal stenosis single-level lumbar fusion surgery, postoperative residual pain to our hospital outpatient clinic patients
Exclusion criteria
Exclusion criteria: 1. The patient is pregnant or lactating 2. Participants who had participated in other drug trials within 30 days of enrollment 3. The researchers considered that participants were not suitable to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The improvement rate of VAS score after 3-month treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| The improvement rate of numbness after 3-month treatment;Improvement rate of ODI at last follow-up;Improvement rate of EQ-5D at last follow-up;Improvement rate of Hamilton depression scale scores and Hamilton Anxiety Rating Scale scores;Time to return to work/life during follow-up;Incidence of adverse events during various treatment periods; | — |
Countries
China
Contacts
Public ContactQingchu Li
The Third Affiliated Hospital of Southern Medical University
Outcome results
None listed