herpes zoster-associated neuralgia
Conditions
Interventions
Ozonated autohemotherapy group (O3-AHT group):On the basis of treatment with oral neurotrophic and analgesic drugs, ozonated autohemotherapy was performed for 5 days (concentration was 25 µg/mL)
Ozone rectal insufflation group (O3-RI group):On the basis of treatment with oral neurotrophic and analgesic drugs, ozone rectal insufflation was treated for 5 days (concentration was 30 µg/mL)
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?The age range is 65 to 80. ?The diagnosis was acute herpes zoster pain or postherpetic neuralgia. ?All patients had moderate to severe pain, VAS score =4. ?The analgesic effect of conventional drug treatment is not ideal. ?Can cooperate with treatment and complete follow-up.
Exclusion criteria
Exclusion criteria: Glucose-6-phosphate dehydrogenase deficiency (favism); Toxic diffuse goiter (Graves' disease); Platelet count lower than 50×10^9/L, severe coagulation disorders; Severe unstable cardiovascular diseases, acute myocardial infarction; Acute alcohol intoxication; Massive blood loss, acute hemorrhage, anemia (<90 g/L); Disturbances of water and electrolyte; Seizure, convulsive state; Hemochromatosis, patients undergoing treatment with copper or iron; Hypersensitivity to anticoagulant (sodium citrate); Syncope due to fear of needles or blood; Severe liver insufficiency; Pregnancy; Previous mental disorders or existing cognitive dysfunctions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| numerical rating scale for pain before and after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| self-rating scale of sleep before and after treatment;Use of analgesic drugs after treatment;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactFang Ming
Affiliated Hospital of Jiangnan University
Outcome results
None listed