A Multicenter Randomized Controlled Study on the Effect of CQI and CPRV Assisted Cardiopulmonary Resuscitation on the Clinical Outcome of Patients with Cardiac Arrest

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400092831

Enrollment

Unknown

Registered

2024-11-25

Start date

2024-12-01

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac arrest

Interventions

CQI combined CPRV group:CQI index guides manual or mechanical chest compressions, tracheal intubation in ACLS stage, and CPRV mode of ventilator ventilation

CQI group:CQI index guides manual or mechanical chest compressions, tracheal intubation in ACLS stage, and VCV mode of ventilator ventilation

Traditional resuscitation group:Manual or mechanical chest compressions, tracheal intubation in ACLS stage, and VCV mode of ventilator ventilation.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with cardiac arrest received by the emergency center, including patients with cardiac arrest outside the hospital and patients with cardiac arrest in the hospital; 2.The time from cardiac arrest to CPR is less than 10 minutes (if cardiac arrest occurs before hospital and is delivered by ambulance, whether the CPR time is more than 10 minutes shall be obtained from the ambulance medical staff); 3. Age > 18 years old;

Exclusion criteria

Exclusion criteria: 1. Age < 18 years old; 2. Pregnant women; 3. Chest trauma affects chest compressions; 4. The patient's family refused cardiopulmonary resuscitation (DNR); 5. Malignant tumor, patients receiving palliative treatment; 6. Patients that the research team thinks are not suitable for resuscitation; 7. fingers or toes can't accurately measure POP; 8. Patients receiving ECMO treatment during resuscitation.

Design outcomes

Primary

Measure	Time frame
Rate of return of spontaneous circulation;	—

Secondary

Measure	Time frame
Cardiopulmonary resuscitation quality index;Partial pressure of end-tidal carbon dioxide value;Start recovery to return of spontaneous circulation time;Vital signs and blood gas analysis parameters during return of spontaneous circulation;Neuron-specific enolase level;Length of ICU stay;Total length of stay;7-day survival rate;30-day survival rate;Cerebral performance category score;	—

Countries

China

Contacts

Public ContactDingyu Tan

Northern Jiangsu People's Hospital

32494845@qq.com+86 180 5106 1672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026