Vascular and circulatory disorders of the digestive system, dysmotility of the digestive tract and functional gastrointestinal diseases
Conditions
Interventions
Goal-directed fluid therapy combined with phenylephrine group(GP):Goal-directed fluid therapy combined with phenylephrine
Goal-directed liquid therapy group (Group G):Goal-directed liquid therapy
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the indications for laparoscopic surgery; 2. Age= 65 years old; 3. ASA classification II-III; 4 .BMI<30kg/m2;
Exclusion criteria
Exclusion criteria: 1. Known to be allergic to anesthetic drugs and test liquids (sodium bicarbonate Ringer's solution, hydroxyethyl starch solution); 2. Patients with a history of esophageal or gastrointestinal surgery in the past; 3. Previous arrhythmia; 4.Hb<70g/l; 5. Albumin<35g/L; 6. Severe cardio-cerebrological, hepatic and renal diseases before surgery; 7. Peripheral vascular disease or contraindication to ductus arteriosus placement;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score at 24h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 scores at 48h and 7d postoperatively;Hemodynamic indicators;Early recovery indicators;Incidence of postoperative complications (pulmonary infection, acute kidney injury, incision infection);Postoperative adverse events; | — |
Countries
China
Contacts
Public ContactQi Dunyi
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed