Spinal cord injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? diagnosis of acute C4 - C8 spinal cord injury and visit within 24 hours of injury; ?Grade A, B, or C on the American Spinal Cord Injury Association (ASIA) Impairment Scale based on initial evaluation; ? 18 to 75 years of age; ? complete medical records, including detailed clinical data, laboratory results, imaging results, and follow-up records during the course of treatment.
Exclusion criteria
Exclusion criteria: 1. SCI due to penetrating injury. 2. Previous history of SCI. 3. Concomitant severe head injury (Glasgow Coma Scale < 14 with clinically significant abnormalities on head CT). 4. Presence of a pre-existing neurological or psychiatric disorder that would affect accurate assessment and follow-up. 5. Has a history of chemical dependence or significant psychosocial disorder (which may affect outcomes or participation) and has been < 1 year. 6. Females of childbearing potential with a positive serum ß - hCG pregnancy test or uterine urine pregnancy test. 7. Have acquired immunodeficiency syndrome or related syndromes. 8. Has an active malignancy or a history of aggressive malignancy within the past 5 years (excluding superficial basal cell carcinoma or squamous cell carcinoma of the skin that has been definitively treated).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale;Spinal perfusion pressure, SCPP;Changes of ASIA grade ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor and sensory function;Anal sphincter function; | — |
Countries
China
Contacts
Affiliated Hospital of Xuzhou Medical University