Atopic dermatitis
Conditions
Interventions
Probiotic formula:Take one sachet of probiotic products daily
Sponsors
The Peoples' Hospital of Tinghu District of Yancheng City
Eligibility
Sex/Gender
All
Age
2 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. meets the diagnosis of AD according to Hanfin and Rajka criteria; 2. 2 years <= age <= 80 years, male or female; 3. good compliance, able to comply with the requirements of the clinical trial; 4. atopic dermatitis assessment by a dermatologist with a SCORAD score of =25 (moderately severe); 5. subjects or guardians have signed the informed consent;
Exclusion criteria
Exclusion criteria: 1. Known hypersensitivity to any of the ingredients in the test drug; 2. patients who have received systemic glucocorticoid therapy within the week prior to the test or phototherapy (e.g., UVB, PUVA) that is suspected to be capable of affecting atopic dermatitis (eczema), or systemic therapy (immunosuppressive agents, cytosolic growth inhibitors); 3. Patients who are immunosuppressed (e.g., lymphoma) or have a history of malignant disease complicated by any dermatological condition that interferes with the evaluation of test results; 4. patients who refuse to sign the informed consent form or who are estimated to have poor compliance and poor likelihood of follow-up; 5. women during pregnancy or lactation; 6. recent (1-3 months) consumption of probiotic products or long-term consumption of yoghurt or probiotic drinks. 7. Recent (1-3 months) or long-term use of antibiotics. 8. Other cases that did not meet the inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| dermatology life quality index, DLQI;SCORAD;Immunological indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal microbes; | — |
Countries
China
Contacts
Public ContactWenwei Lu, Yanni Wang
Jiangnan University; People's Hospital of Tinghu, Yancheng
Outcome results
None listed