Chronic heart failure
Conditions
Interventions
Anti-heart failure pellet group:On the basis of standardized western medicine treatment, anti-heart failure granules were combined with the following medicines: Astragalus 30g, Maitong 15g, Cornu Cerv
Individualized Aerobic Training Group:Individualized aerobic training was combined with standardized western drug therapy, and the aerobic training protocol was developed based on CPET results.
Anti-heart failure pellet group combined with aerobic training group:Co-administration of anti-heart failure particles and CPET aerobic training on the basis of standardized western drug therapy.
Sponsors
Changzhou De'an Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Meet the above diagnostic standards of Chinese and Western medicine; 2. Age 50-85 years old; 3. NYHA cardiac function grade II.~IV; 4. Left ventricular ejection fraction (LVEF) <50%; 5. Receiving at least 2 weeks of standardized drug treatment; 6. All study subjects signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Heart failure caused by congenital heart disease, acute heart failure, or heart failure after acute myocardial infarction; 2. Those who plan to undergo coronary revascularization therapy and cardiac resynchronization therapy within 8 weeks; 3. Patients with myocarditis, aneurysm, left ventricular outflow tract obstruction and unrepaired valvular heart disease with obvious hemodynamic changes; 4. Patients with cardiogenic shock, uncontrollable malignant arrhythmia, sinus or atrioventricular block of second degree or more without pacemaker treatment, progressive aggravation of unstable angina pectoris or acute myocardial infarction; 5. Patients with pulmonary infection, tumors, mental illness, severe hematological, nervous and endocrine diseases; 6. Patients with severe primary diseases of liver and kidney, and severe abnormalities of liver and kidney function; 7. Patients with uncontrolled hypertension, systolic blood pressure = 180mmHg and/or diastolic blood pressure = 110mmHg; 8. Those who have participated in other drug clinical studies within 1 month; 9. Women who are pregnant or preparing to become pregnant and lactating; 10. Those with allergies, or those who are known to be allergic to therapeutic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese Medicine Score;NYHA Cardiac Functional Classification;Cardiopulmonary Exercise Test Indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Minnesota Quality of Life Questionnaire;Echocardiographic indicators;Serological test; | — |
Countries
China
Contacts
Public ContactJia Li
Changzhou De'an Hospital
Outcome results
None listed