Lung cancer
Conditions
Interventions
Group P:After the right lateral decubitus position, 0.1µg/kg PGE1 (diluted to 10 ml of normal saline) was atomized into the right lung.
Group C:After the right lateral decubitus position, aerosolized saline 10 ml was atomized into the right lung.
Sponsors
Nanjing Meishan Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 84 Years
Inclusion criteria
Inclusion criteria: Sixty patients of both sexes, aged 65-84 yr, with body mass index of 18-28 kg/m2, scheduled for elective radical resection of left lung cancer (single lobe/segment), were enrolled
Exclusion criteria
Exclusion criteria: Previous lung surgery history and preoperative neoadjuvant chemotherapy; The patient had a history of upper respiratory tract infection and severe COPD two weeks before surgery. There was severe dysfunction of important organs such as heart, liver and kidney before operation. There were senile dementia and cognitive impairment before operation. History of glaucoma or allergy to PGE1.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intrapulmonary shunt; | — |
Secondary
| Measure | Time frame |
|---|---|
| Index of oxygenation;Airway peak pressure;Airway plateau pressure;Cdyn;Mean arterial pressure;Heart rate; | — |
Countries
CHINA
Contacts
Public ContactQiang Wang
Nanjing Meishan Hospital
Outcome results
None listed