Cardiac insufficiency
Conditions
Interventions
The recombinant human brain natriuretic peptide was pumped separately(0.0075µg/kg/min, adjusted according to blood pressure, no more than 3 days) :None
Recombinant human brain natriuretic peptide (0.0075µg/kg/min for 3 days) combined with metaraminol bitartrate injection (1-5mg/h, adjusted according to blood pressure):None
Recombinant human brain natriuretic peptide (0.0075µg/kg/min for 3 days) combined with dopamine hydrochloride injection (1-5µg/kg/min, adjusted according to blood pressure):None
Sponsors
Aerospace Center Hospital
Eligibility
Sex/Gender
All
Age
80 Years to 100 Years
Inclusion criteria
Inclusion criteria: ? Age >= 80 years old ? Diagnosis of cardiac insufficiency (Framingham heart failure diagnostic criteria), with NYHA grade greater than Grade II. ? Meet the indication of using recombinant human brain natriuretic peptide. ? Basic systolic blood pressure at admission is 90-110mmHg. ? Voluntary participation and filling in the informed consent form (Ethics Committee of Aerospace Center Hospital)
Exclusion criteria
Exclusion criteria: ? Patients with cardiac insufficiency in non-clinical heart failure stage. ? Hemorrhagic shock ? Severe hepatic and renal insufficiency. ? Critical patients with unconsciousness and unstable vital signs. ? Patients who can't complete the treatment and observation due to the change of their condition or the change of the wishes of patients and their families.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BNP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Data of cardiac color Doppler ultrasound;6-minute walking distance;MACE; | — |
Countries
China
Contacts
Public ContactRui Meng
Aerospace Center Hospital
Outcome results
None listed