gestational
Conditions
Interventions
The paracetamol and mannitol injection group:Intravenous paracetamol and mannitol injection
The placebo group:Intravenous infusion of normal saline
Sponsors
Hangzhou Women's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1.primiparous parturients; 2.ASA I and II; 3.aged 18–35 years; 4.spontaneous onset of labour at term (37–42 weeks gestation); 5.with cervical dilatation of 5 cm; 6.a single live foetus in cephalic presentation;
Exclusion criteria
Exclusion criteria: 1.refusal by parturient; 2.parturients who had received parenteral opioids in the last four hours; 3.deranged coagulation profile; 4.multiple pregnancies; 5.premature labour; 6.obstetric complications (e.g., premature rupture of amniotic membranes) and allergy to study drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hourly average consumption of ropivacaine and fentanyl mixture; | — |
Secondary
| Measure | Time frame |
|---|---|
| mode of delivery;Apgar scores;maternal satisfaction;Baseline characteristics : Age, height, weight and so on;sensory and motor block characteristics;visual analogue scale;foetal heart rate and adverse effects;haemodynamic parameters of mother;Duration of second stage of labour; | — |
Countries
China
Contacts
Public ContactZhou Zhenfeng
Hangzhou Women's Hospital
Outcome results
None listed