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The effect of liposomal bupivacaine for thoracolumbar interfascial plane on postoperative recovery quality and opioid dosage in lumbar spine surgery

The effect of liposomal bupivacaine for thoracolumbar interfascial plane on postoperative recovery quality and opioid dosage in lumbar spine surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400092765
Enrollment
Unknown
Registered
2024-11-22
Start date
2025-01-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar spine disease

Interventions

Sponsors

Fuyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ASA Level I-II; 2. Age range: 18-75 years old; 3. BMI 18-30 kg/m^2 ; 4. After fully explaining the content of the clinical trial, patients and their families voluntarily joined and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Preoperative Mini Mental State Examination (MMSE) score <= 25 points; 2. History of neurological disorders, mental illnesses, and cardiovascular diseases; 3. History of allergy to local anesthetics; 4. Have a history of dependence on painkillers and drug use; 5. Patients with infection at the puncture site and abnormal coagulation function.

Design outcomes

Primary

MeasureTime frame
Total postoperative sufentanil dosage;

Secondary

MeasureTime frame
adverse reaction;Time of first use of analgesics after surgery;VAS pain scores during rest and turning after surgery;PCIA effective compression frequency, dose of additional flurbiprofen axetil;Postoperative recovery quality;Postoperative incidence of chronic pain;

Countries

China

Contacts

Public ContactMa Xingjun

Fuyang People's Hospital

maxj1234@163.com+86 13955899119

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026