ischemic stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged 18 years and above; (2) Frequently residing in high-altitude areas of western Sichuan (the altitude of the permanent residence area is higher than 1500 meters); (3) Clinical diagnosis of AIS and the presence of large vessel occlusion confirmed by CTA/DSA; (4) The time interval between the last normal time and the group was within 24 hours; (5) Signed informed consent and able to cooperate with the examination and complete the study.
Exclusion criteria
Exclusion criteria: (1) Pre-onset mRS score >2; (2) Combined intracranial hemorrhage or preexisting large cerebral infarction manifestation confirmed by CT/MRI; (3) Clinical history, previous imaging or clinical judgment suggestive of craniocerebral tumor, arteriovenous malformation, or intracranial artery entrapment; (4) History of head trauma in the previous 3 months; (5) Suffering from severe cardiovascular disease, respiratory disease, endocrine disease and other chronic diseases, malignant tumors or life expectancy less than 6 months; (6) Platelets 3.0. (7) Pregnant or lactating women; (8) Suffering from severe mental illness or cognitive impairment that prevents them from cooperating with the study; (9) Already participating in other clinical studies; (10) Other conditions deemed by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of subjects with neurologic recovery to functional independence at 90 days after disease onset; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional ending;death;Revascularization rate;Neurological function improvement rate;Quality of life assessment;Cognitive function assessment;Infarct volume within 5-7 days(Imaging indicators); | — |
Countries
China
Contacts
Ya'an People's Hospital