Epilepsy
Conditions
Interventions
Retrospective cohort, late-onset epilepsy without cognitive impairment:This is an observational study, no intervention would be involved
Retrospective cohort, late-onset epilepsy with cognitive impairment:This is an observational study, no intervention would be involved
Retrospective cohort, non-late-onset epilepsy without cognitive impairment:This is an observational study, no intervention would be involved
Retrospective cohort, non-late-onset epilepsy with cognitive impairment:This is an observational study, no intervention would be involved
Retrospective cohort, healthy controls:This is an observational study, no intervention would be involved
Prospective cohort, late-onset epilepsy without cognitive impairment:This is an observational study, no intervention would be involved
Prospective cohort, late-onset epilepsy with cognitive impairment:This is an observational study, no intervention would be involved
Prospective cohort, cognitive impairment without epilepsy:This is an observational study, no intervention would be involved
Prospective cohort, healthy controls:This is an observational study, no intervention would be involved
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients who had a confirmed diagnosis of epilepsy according to the International League Against Epilepsy 2014 diagnostic criteria; (2) Patients who had their first seizures after the age of 55 with no prior history of seizures or epilepsy; (3) Patients who voluntarily participated in the study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who had a history of major neurological diseases or mental disorders; (2) Patients who had a history of brain surgery; (3) Patients who had acute and reversible cognitive impairment due to significant systemic diseases or encephalopathy; (4) Patients who had a diagnosis of reflex epilepsy; (5) Patients who refuse to follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognition screening;Electroencephalography; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographics;Past medical history;Seizure related history;Medication;Neuroimaging; | — |
Countries
China
Contacts
Public ContactDong Zhou
West China Hospital, Sichuan University
Outcome results
None listed