Primary aldosteronism
Conditions
Interventions
Primary aldosteronism group:Primary aldosteronism
Sponsors
Wuxi people’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1.Patients>=18 years of age, informed consent, diagnosed with primary aldosteronism and willingness to undergo surgery, meet one of the following criteria; 2.Adrenal CT showing the presence of multiple nodular or hyperplastic lesions unilaterally or bilaterally; 3.Adrenal CT showing unilateral or bilateral nodular hyperplasia. 4.Adrenal CT showed a unilateral single nodule except for young patients age 35 years with a combination of spontaneous hyperkalemia marked hypersecretion of aldosterone and CT features consistent with a unilateral adenoma according to international guidelines and except for patients with a plasma aldosterone concentration of 20 ngdL a plasma renin concentration of 5 IUmL a plasma potassium concentration of 3.5 mmolL and an adrenal unilateral nodule of 1 cm in diameter contralateral side was normal according to a national study;
Exclusion criteria
Exclusion criteria: 1.Combination of severe hepatic insufficiency congenital heart disease malignant tumors and severe infections; 2.Patients with severe mental illness or cognitive impairment; 3.Not easy to follow up, not able to provide informed consent, etc. 4.Those who, in the opinion of the researcher, are not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma aldosterone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma renin;Blood pressure;Serum potassium;Plasma cortisol;Plasma adrenocorticotropic hormore; | — |
Countries
China
Contacts
Public ContactXiaowei Zhu
Wuxi people’s Hospital
Outcome results
None listed