Epilepsy
Conditions
Interventions
Subclinical epileptoid discharges group:None
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
1 Months to 16 Years
Inclusion criteria
Inclusion criteria: (1) The age of the patient ranges from 1 month to 16 years old; (2) Children diagnosed with epilepsy (of any type) according to ILAE criteria, or with epileptic discharges without seizures according to the International Federation of Clinical Neurophysiology criteria, accompanied by comorbid neurodevelopmental disorders (NDDs), including intellectual developmental disorders (DID), autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), etc; (3) Prescription LCM as initial monotherapy (4) Parents/guardians provide written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1.Progressive central nervous system (CNS) disease; 2.Allergy to any component of LCM; 3.With congenital heart disease, cardiac sodium channel disease, or cardiac arrhythmia with significant hemodynamic impact; 4.Pregnancy or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retention time of LCM;The number of SEDs per 10 seconds; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time to first seizure;Seizure freedom rate at 12 months of follow-up; | — |
Countries
China
Contacts
Public ContactXiao Nong
Children's Hospital of Chongqing Medical University
Outcome results
None listed