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The safety and efficacy of small-diameter vascular prosthesis loaded with Tgfbr2 gene modified exosomes

The safety and efficacy of small-diameter vascular prosthesis loaded with Tgfbr2 gene modified exosomes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092690
Enrollment
Unknown
Registered
2024-11-21
Start date
2024-11-12
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Carotid artery decortication group:NA

Sponsors

Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age =18 years old; 2.Carotid endarterectomy; 3.Informed consent was obtained;

Exclusion criteria

Exclusion criteria: 1 month participated in other clinical trials and seriously affected this study; 1.Those with other conditions deemed by the investigator to be unsuitable for enrollment;

Design outcomes

Primary

MeasureTime frame
Expression levels of TGFBR2 and key proteins of its signaling pathway;—

Secondary

MeasureTime frame
The changes of matrix deposition;—

Countries

China

Contacts

Public ContactYongchun Cui

Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College

cuiyongchun@fuwaihospital.org+86 10 60866386

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026